Aaryn Ellenberg drained a 3-pointer to start a 15-2 run in the second half that broke open a tight game and sent Oklahoma to its first win in Ames since 2008, pounding No. 20 Iowa State 75-54 Tuesday night.
The win avenged an overtime loss to the then 14th-ranked Cyclones Jan. 5 at Oklahoma.
Ellenberg drained four 3-pointers en route to 22 points and eight rebounds. She scored 10 in the breakaway run deep in the second half, and also guarded Iowa State's Jadda Buckley (who went off for a career-high 29 on Jan. 5), holding her scoreless.
Nicole Griffin scored 12 and Sharane Campbell 10 with nine rebounds for the Sooners (12-7, 3-3 Big 12). Oklahoma outscored Iowa State 36-22 in the paint.
The Cyclones (14-4, 3-4), who have lost their last four, were led by Nikki Moody's 18 points. Hallie Christofferson fouled out with 15 points.
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