Phil Forte scored 20 points - seven of those during a decisive seven-minute stretch in the second half - and Oklahoma State kicked off the Big 12 Conference schedule with a 61-47 victory over Kansas State on Saturday.
Le'Bryan Nash scored 11 points and had six rebounds for the Cowboys (11-2, 1-0 Big 12).
Thomas Gipson scored 14 points to lead Kansas State (7-7, 0-1), which lost its third straight contest.
Trailing 29-27 at halftime, Oklahoma State made a strong push early in the second half, going on a game-changing 25-4 run that included 15-straight points. The Cowboys built up a 54-37 lead after Jeff Newberry connected on a 3 from the left baseline with 11:16 to go.
The game hadn't seen more than a six-point lead before that OSU run.
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